Current Research and Clinical Trials in Acne
www.ClinicalTrials.gov for a list of current acne research opportunities.


Rank Status Study
1 Completed Safety and Efficacy of MBI 226 1.25% and 2.5% Topical Acne Solutions in the Treatment of Acne

Conditions: Acne Vulgaris;   Acne;   Propionibacterium Acnes
Intervention: Drug: MBI 226 Acne Solutions
2 Completed Safety and Efficacy of MBI 226 2.5% and 5.0% Topical Acne Solutions in the Treatment of Acne

Conditions: Acne Vulgaris;   Acne;   Propionibacterium Acnes
Intervention: Drug: MBI 226 Acne Solutions
3 Active, not recruiting Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne

Condition: Acne
Interventions: Drug: Antibiotic and benzoyl peroxide gel;   Drug: Antibiotic and topical retinoid gel
4 Completed A Study of Acne Treatment in Children Ages 9 to 11

Condition: Acne Vulgaris
Interventions: Drug: Retin-A Micro 0.04% facial acne treatment;   Drug: Vehicle control
5 Completed Comparison Study of Topical Acne Regimens

Condition: Acne
Intervention: Drug: Acne Free, Proactiv
6 Terminated Pilot Study of a Dietary Intervention to Prevent Acne Recurrence

Condition: Acne
Intervention: Behavioral: Minimization of milk and dairy products in the diet
7 Active, not recruiting Plant-based Dietary Intervention for Treatment of Acne

Condition: Acne
Interventions: Behavioral: Low-fat, vegan diet;   Behavioral: Control
8 Terminated Photodynamic Therapy in the Treatment of Acne

Condition: Acne Vulgaris
Intervention: Device: LumaCare LC-122M non-coherent light source with LUM-I, fiber optic probe, 610 nm-660 nm output range
9 Recruiting Safety and Efficacy of Skin Cleanser Contained Roselle Extract in Acne

Condition: Acne
Interventions: Other: skin cleanser contained Hibiscus sabdariffa extract;   Other: marketed skin cleanser
10 Recruiting Efficacy of Lappa Arctium (Homoeopathic Medicine) in Treatment of Acne Vulgaris

Condition: Acne Vulgaris
Intervention: Drug: Lappa Arctium
11 Active, not recruiting Adherence to Study Medication Compared to Generic Topical Clindamycin Plus Generic Topical Tretinoin in Subjects With Mild to Moderate Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Drug: clindamycin phosphate 1.2% and tretinoin 0.025%;   Drug: clindamycin 1% gel plus tretinoin 0.025%
12 Completed A Study of Different Use Regimens Using Two Acne Treatments

Condition: Acne Vulgaris
Intervention: Drug: benzoyl peroxide wash and tretinoin gel
13 Completed Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne

Condition: Acne
Interventions: Drug: Benzoyl peroxide with clindamycin;   Drug: Benzoyl peroxide with clindamycin and doxycycline
14 Active, not recruiting A Study to Compare the Tolerability and Efficacy of Tazorac Cream Used With Duac Gel or Acanya Gel for Treatment of Acne

Condition: Acne Vulgaris
Interventions: Drug: Tazorac Cream and Duac Topical Gel;   Drug: Tazorac Cream (tazarotene 0.1%) plus Acanya Gel (clindamycin phosphate 1.2%/benzoyl peroxide 2.5%).
15 Terminated
Has Results
Efficacy And Safety Of Azithromycin SR Compared With Minocycline In Acne

Condition: Acne Vulgaris
Interventions: Drug: Azithromycin microspheres;   Drug: minocycline-placebo capsules;   Drug: Azithromycin microspheres-placebo;   Drug: Minocycline capsules,
16 Active, not recruiting NdYag Laser for Acne Keloidalis Nuchae

Conditions: Acne Keloidalis Nuchae;   NdYag Laser;   AKN;   Acne Keloidalis;   AK;   Dermatitis Papillaris Capillitii;   Folliculitis Keloidalis Nuchae;   Sycosis Nuchae;   Acne Keloid;   Keloidal Folliculitis;   Lichen Keloidalis Nuchae;   Folliculitis Nuchae Scleroticans;   Sycosis Framboesiformis
Interventions: Device: NdYag Laser(hair removal laser) plus topical corticosteroid;   Drug: Topical corticosteroid alone
17 Recruiting A Study to Examine the Safety and Efficacy Of Drospirenone and Ethinyl Estradiol (YAZ) Compared With Placebo In The Treatment Of Moderate Truncal Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Drug: drospirenone and ethinyl estradiol;   Drug: Placebo tablets
18 Completed Microdermabrasion for Acne

Condition: Acne Vulgaris
Intervention: Device: microdermabrasion
19 Enrolling by invitation Proof of Concept Study to Investigate the Recurrence of Acne Post Isotretinoin

Condition: Acne
Interventions: Drug: tretinoin microsphere 0.04% gel;   Drug: vehicle gel
20 Completed Infrared Non-Cutting Laser Therapy for Acne

Condition: Acne Vulgaris
Intervention: Device: CoolTouch II laser
21 Active, not recruiting Non-Cutting Laser Therapy in the Treatment of Acne

Condition: Acne Vulgaris
Intervention: Device: V-Beam laser, Candela Corp., 595 nm wavelength
22 Completed Study of Two Different 10.0% Benzoyl Peroxide Creams for Mild to Moderate Acne Vulgaris

Condition: Acne Vulgaris
Intervention: Drug: topical benzoyl peroxide 10.0% cream – Formulations #1 and #2
23 Active, not recruiting Trial of Clindamycin / Benzoyl Peroxide Gel in Subjects With Acne

Condition: Acne Vulgaris
Interventions: Drug: clindamycin / benzoyl peroxide gel;   Drug: clindamycin gel;   Drug: BPO gel;   Drug: vehicle gel
24 Completed Safety and Efficacy Study of Topical Methyaminlevulinate (MAL) in Subjects With Facial Acne

Condition: Acne
Intervention: Drug: MAL
25 Completed A Split-Face, Paired-Comparison, Pilot Study to Evaluate Safety and Efficacy of Two Topical Salicylic Acid 1.0% Creams for Mild to Moderate Acne Vulgaris

Condition: Acne Vulgaris
Intervention: Drug: topical salicylic acid 1.0% cream
26 Completed Comparison of Efficacy and Safety of Azelaic Acid 15% Gel With Its Vehicle in Subjects With Mild to Moderate Acne

Condition: Acne Vulgaris
Interventions: Drug: Azelaic Acid Gel 15% (Finacea, BAY39-6251);   Drug: Vehicle gel (SH H 655 PBA)
27 Completed Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Drug: Epiduo Gel;   Drug: Duac Gel
28 Completed A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne

Condition: Acne Vulgaris
Interventions: Drug: clindamycin and benzoyl peroxide gel (Duac® Topical Gel);   Drug: benzoyl peroxide and adapalene gel (EPIDUO™ Gel)
29 Recruiting the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of Acne Vulgaris

Condition: Acne
Interventions: Drug: Doxycycline;   Drug: Azithromycin
30 Completed Comparison of Stacked-Pulses Vs. Double-Pass Treatments of Facial Acne With a 1450 Nm Laser

Conditions: Acne;   Acne Scars
Intervention: Device: 1450nm diode laser
31 Completed Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD Deficiency

Condition: Acne Vulgaris
Interventions: Drug: ACZONE Gel, 5%;   Drug: Vehicle
32 Recruiting Safety and Efficacy of the Use of Botox on Acne

Condition: Acne Vulgaris
Interventions: Drug: Botulinum Neurotoxin Type A;   Drug: Bacteriostatic saline
33 Completed Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris

Condition: Acne Vulgaris
Intervention: Drug: Adapalene/Benzoyl Peroxide
34 Recruiting A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne

Condition: Acne Vulgaris
Interventions: Drug: Tazarotene Foam;   Drug: Vehicle Foam
35 Completed Fractional Resurfacing Device for Treatment of Acne Scarring

Condition: Acne Scarring
Intervention: Device: 10,600 nm fractional CO2 laser system
36 Active, not recruiting Efficacy & Safety of Clindamycin and Tretinoin in Acne

Condition: Acne
Intervention: Drug: Clindamycin Phosphate 1.2% and Tretinoin 0.025% Gel
37 Completed A Phase 2 Study of ASC-J9 Cream in Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Drug: ASC-J9 cream;   Drug: placebo
38 Completed Study of Benzoyl Peroxide Cream for Mild to Moderate Acne Vulgaris

Condition: Acne Vulgaris
Intervention: Drug: Benzoyl Peroxide
39 Completed Measuring Adherence in Subjects With Acne Vulgaris in a Clinic Population Subtitle: Topical Benzoyl Peroxide for Acne

Condition: Acne Vulgaris
Intervention: Drug: Benzoyl Peroxide
40 Active, not recruiting Safety and Efficacy of 1550nm Fractional Laser Treatment for Acne Scars in Fitzpatrick Type IV-VI Skin

Condition: Acne Scarring
Intervention: Procedure: Fractionated Laser Resurfacing
41 Completed Safety and Efficacy Study of Clindamycin/Benzoyl Peroxide/Tazarotene Cream in Subjects With Acne

Condition: Acne Vulgaris
Interventions: Drug: Benzoyl peroxide/clindamycin gel + tazarotene cream;   Drug: Benzoyl peroxide/clindamycin gel + vehicle cream;   Drug: Benzoyl peroxide gel + tazarotene cream;   Drug: Clindamycin gel + tazarotene cream;   Drug: Vehicle gel+ tazarotene cream;   Drug: Vehicle gel + vehicle cream
42 Recruiting Apremilast in the Treatment of Moderate to Severe Acne

Condition: Acne
Intervention: Drug: apremilast
43 Completed
Has Results
Treatment of Acne Vulgaris With Doryx Tablets Compared to Doxycyline Hyclate

Condition: Acne Vulgaris
Interventions: Drug: Doxycycline hyclate (Doryx);   Drug: Doxycycline hyclate
44 Not yet recruiting Safety and Efficacy Study of Acnase Creme in the Treatment of Acne Vulgaris I and II

Condition: Acne Vulgaris
Interventions: Drug: Benzoyl Peroxide 5% and Sulphur 2%;   Drug: Vehicle of Acnase
45 Recruiting Study to Compare the Acne Relapse Rate of Oral Minocycline to Oral Minocycline in Combination With Topical Tretinoin, Followed by Topical Tretinoin Alone

Condition: Acne Vulgaris
Interventions: Drug: Minocycline;   Drug: Minocycline + Tretinoin 0.01%
46 Active, not recruiting Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation

Conditions: Acne Vulgaris;   Post Inflammatory Hyperpigmentation
Intervention: Drug: Azelaic acid
47 Completed The Development and Evaluation of an “E-Visit” Program for the Management of Acne

Condition: Acne Vulgaris
Interventions: Other: Evisit;   Other: Office visit
48 Completed Pulsed Dye Laser Treatment of Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Drug: Fixed combination of clindamycin 1% + benzoyl peroxide 5%;   Device: Pulsed dye laser
49 Withdrawn The Treatment of Acne Vulgaris With Radiofrequency Device

Condition: Acne Vulgaris
Intervention: Device: Radio Frequency
50 Completed Efficacy and Tolerance of a Derivative of Salicylic Acid and 5% Benzoyl Peroxide in Facial Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Drug: Lipo Hydroxy Acid;   Drug: 5% benzoyl peroxide gel
51 Terminated Topical 5-ALA-PDT With Blu-U Therapy Versus Topical 5-ALA With Pulse Dye Laser In Treating Recalcitrant Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Drug: 5-ALA with Blu-U Light;   Drug: 5-ALA with Candela V-beam Pulse Dye Laser
52 Completed A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of Acne

Condition: Acne Vulgaris
Interventions: Drug: BENZOYL PEROXIDE/ CLINDAMYCIN;   Drug: BENZOYL PEROXIDE/ ADAPALENE
53 Completed Evaluate Safety & Efficacy of an OC Preparation vs Placebo for 6 Treatment Cycles in Women With Moderate Acne

Condition: Acne Vulgaris
Interventions: Drug: YAZ (DRSP 3 mg/EE 0.02 mg, BAY86-5300);   Drug: Placebo
54 Completed Evaluate Safety & Efficacy of an Oral Contraceptive (OC) Preparation Versus Placebo for 6 Treatment Cycles in Women With Moderate Acne

Condition: Acne Vulgaris
Interventions: Drug: YAZ (DRSP 3 mg/EE 0.02 mg, BAY86-5300);   Drug: Placebo
55 Recruiting A Study to Evaluate the Efficacy of Silk – Like Bedding Fabric, as Used in a Standard Pillow Case, in the Treatment of Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Device: silk-like fabric standard pillowcase;   Device: pillowcase made of 100% cotton
56 Recruiting “A Randomized, Controlled, Evaluator-blinded Pilot Study to Evaluate the Effect of Automated Text Message Reminders on Patient Compliance With Topical Medications and Its Efficacy on Skin Disease Control in Adolescents and Adults With Mild to Moderate Acne”

Conditions: Acne;   Patient Compliance
Intervention: Other: Text message reminders
57 Completed Safety and Efficacy Study of Association Between Tretinoin and Clindamycin on the Treatment of Acne Mild and Moderate

Condition: Acne Vulgaris
Intervention: Drug: application of the topic gel
58 Recruiting Exploratory Study to Evaluate the Efficacy and Safety of CD07223 Gel in Subjects With Acne

Condition: Acne
Intervention: Drug: Epiduo vehicle gel
59 Completed
Has Results
A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris

Condition: Acne Vulgaris
Interventions: Drug: Adapalene/Benzoyl Peroxide;   Drug: Adapalene;   Drug: Benzoyl Peroxide;   Drug: Topical Gel Vehicle
60 Not yet recruiting Open and Comparative Study to Measure Tolerability and Efficacy of Taro Elixir

Conditions: Acne Vulgaris II or III Degree;   Boils
Interventions: Drug: oxytetracycline, taro elixir;   Drug: Taro Elixir